The four main research projects within TREC@WUSTL examine how preconception diet, nutrition and built environment impact inactivity, and how physical activity and energy balance influence body weight and carcinogenesis across the life course.
|TREC@WUSTL Research Projects|
|Project One – Transgenerational animal models of nutritional impact on cancer predisposition|
Investigates, in a mouse model, the effect of maternal high fat diet and changes in metabolic bioenergetics.
|Project Two – PIE (Prostatectomy, Incontinence and Erectile function)|
Studies the role of physical activity and obesity in post-prostatectomy urinary and sexual function.
|Project Three – SHOW-ME Study (Supports at Home and Work for Maintaining Energy Balance)|
Studies policies relating to nutrition and built environment that impact energy balance and obesity.
|Project Four – Social determinants in the link between obesity and cancer|
Develops models of obesity across the life course and generations incorporating biologic, clinical and social determinants of risk and mortality, which can be applied to different cancer outcomes using non-Hodgkin’s lymphoma as the initial platform.